Clobetasol

Medicine Guide
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Drug Class

Corticosteroid

Common Uses

Severe resistant inflammatory skin disorders such as:

  • Frequently relapsing eczema​
  • Psoriasis
  • Lichen Planus
  • Dermatitis or other skin conditions (not responsive to milder steroids)

Common Brand Names

Clobmarksans, Cloderm, Clorip, Hofvate, Clobet, Clinoderm, ClobaDerm, Dermovate, Etrivex

Overview

Clobetasol is a steroid medicine that's used on the skin to treat swelling, itching and irritation. Although it is a steroid, it's not the same as anabolic steroids.

Clobetasol is a very strong steroid. It works by reducing the swelling (inflammation), itching and pain caused by an allergic reaction or irritation.

It can help with skin problems such as:

  • eczema, including contact dermatitis
  • psoriasis
  • lichen planus
  • lupus (discoid lupus erythematosus)

Clobetasol is available on prescription only in some countries.

It comes as a cream, ointment, scalp treatment and shampoo.

There is also a cream and ointment called clobetasone which sounds similar to clobetasol. Clobetasone is much milder and you can buy it from pharmacies or shops.

Clobetasol is also available as a medicine combined with an antibiotic (neomycin sulfate) and an antifungal (nystatin). This is only available on prescription.

Important Facts

  • Do not put clobetasol on your face unless your doctor says it's OK. It can make some skin problems on the face worse.
  • Clobetasol starts to work after a few days. You can use it for up to 4 weeks.
  • If you have applied clobetasol to your skin, wait at least 30 minutes before using another product, like a moisturiser.
  • If your doctor has prescribed high doses of clobetasol to control your symptoms you may need to carry a steroid emergency card. Ask your pharmacist or doctor if this is available in your country.
  • Dried skin cream on your clothes or bedding makes them more likely to catch fire (flammable). Avoid naked flames.
  • If you use clobetasol for a long time your doctor might advise you to reduce your dose gradually to avoid withdrawal reactions.

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Checked & Approved
Clinical Review Team
Written & Translated
Medical Publishing Team
Last Updated
16 March 2025
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