Promethazine

Medicine Guide
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Drug Class

Sedating Antihistamine

Common Uses

  • Allergies
  • Insomnia

Common Brand Names

Phenergan

Overview

Promethazine is an antihistamine medicine that relieves the symptoms of allergies.

It's known as a drowsy (sedating) antihistamine, so it's more likely to make you feel sleepy than other antihistamines.

Promethazine is used for:

  • short-term sleep problems (insomnia) – including when a cough, cold or itching is keeping you awake at night
  • allergies, including hay fever and hives (urticaria)
  • feeling and being sick (vomiting) – due to motion sickness or vertigo
  • cold symptoms, such as coughing and a runny nose

Important Facts

  • Do not drink alcohol while taking promethazine. Alcohol increases the risks of side effects.
  • To help you sleep, take promethazine 20 minutes before you go to bed. It normally takes about 30 minutes to work.
  • To prevent motion sickness, take promethazine the night before a long journey or 1 to 2 hours before a short journey.
  • Common side effects of promethazine include drowsiness, headaches, nightmares and feeling dizzy, restless or confused.

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Checked & Approved
Clinical Review Team
Written & Translated
Medical Publishing Team
Last Updated
19 December 2024
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